Parahexyl

Parahexyl (Synhexyl, n-hexyl-ΔTHC) is a synthetic homologue of THC, which was invented in 1949 during attempts to elucidate the structure of Δ-THC, one of the active components of cannabis.

Parahexyl is similar in both structure and activity to THC, differing only in the position of one double bond, and the lengthening of the 3-pentyl chain by one CH₂ group to n-hexyl. Parahexyl produces classic cannabis agonist effects in animals. It has a somewhat higher oral bioavailability than THC itself but is otherwise very similar. Presumably it acts as a CB₁ agonist in the same way as THC but as there has been no research published using Parahexyl since the discovery of the CB₁ receptor this has not been definitively confirmed.