Retrogenesis

Retrogenesis (also known as retro-genesis) is a medical term used to describe a scientific hypothesis about the development and progress of Alzheimer's disease (AD), an affliction that features a variety of severe symptoms relating to brain function. Historically, AD has been linked to gray matter atrophy, but recently the theory of retrogenesis suggests that AD could be due to white matter atrophy, as well. Human neuropathological studies have determined that AD impairs tens of millions of people worldwide, with cognitive abilities suffering in victims as the structure of minute tissues within their brain becomes altered. Retrogenesis breaks down AD into specific mechanisms that characterize signs of cognitive and functional degeneration. Giving the patients the best, most effective care has been seen as a difficult issue given the radically negative changes that AD can cause in people's life skills. The retrogenesis hypothesis assumes that white matter atrophy takes place within the human nervous system with changes, such as myelin breakdown and axonal damage taking place.