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词汇 Maturity onset diabetes of the young
分类 英语词汇 英语翻译词典
释义

Maturity onset diabetes of the young

英语百科

Maturity onset diabetes of the young

Maturity onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production. MODY is often referred to as "monogenic diabetes" to distinguish it from the more common types of diabetes (especially type 1 and type 2), which involve more complex combinations of causes involving multiple genes (i.e., "polygenic") and environmental factors. MODY 2 and MODY 3 are the most common forms. " MODY should not be confused with latent autoimmune diabetes of adults (LADA) a form of type 1 DM, with slower progression to insulin dependence than child-onset type 1 DM, and which occurs later in life.

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