Hunting reaction

The hunting reaction or hunting response is a process of alternating vasoconstriction and vasodilation in extremities exposed to cold. The term Lewis reaction is used too, named after Thomas Lewis who first described the effect in 1930.

Vasoconstriction occurs first to reduce heat loss, but also results in strong cooling of the extremities. Approximately five to ten minutes after the start of cold exposure, the blood vessels in the extremities will suddenly vasodilate. This is probably caused by a sudden decrease in the release of neurotransmitters from the sympathetic nerves to the muscular coat of the arteriovenous anastomoses due to local cold. This cold-induced vasodilation increases blood flow and subsequently the temperature of the fingers. A new phase of vasoconstriction follows the vasodilation, after which the process repeats itself.