Councilman body

In pathology, a Councilman body, also known as Councilman hyaline body or apoptotic body, is an acidophilic (eosinophilic / pink-staining on H&E) globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma. They are found in the liver of individuals suffering from viral hepatitis (acute), yellow fever, or other viral syndromes. It represents a hepatocyte that is undergoing necrosis/apoptosis. Liver biopsy of acute viral hepatitis typically shows panlobular lymphocytic infiltrates with ballooning hepatocytes (indicative of hepatocyte necrosis and hepatocyte apoptosis).