In essential thrombocythemia there's a genetic mutation that occurs in the Janus Kinase 2 gene, also called JAK2, or somewhere along this pathway of cell signalling.

患有原发性血小板增多症时，Janus Kinase 2（JAK2）基因或这条细胞信号转导通路的某处发生了基因突变。

Using these partial models, they can study things like cell signalling, or even the formation of the primitive streak - the crucial thread of cells which guides the process called gastrulation.

使用这些部分模型，他们可以研究细胞信号传导，甚至原始条纹的形成 - 细胞的关键线程，它指导称为原肠胚形成的过程。