Markers are substances released into the bloodstream upon death of cardiac myocytes.

标记物是心肌细胞死亡后释放到血液中的物质。

However because calcium is also involved in cardiac myocyte contraction, these agents also reduce contractility of the heart and should not be used in case of systolic heart failures.

然而，因为钙通道也参与了心肌收缩，所以这些药物也会减弱心脏的收缩力，因此收缩性心力衰竭患者不应该使用该类药物。