博布鲁伊斯克（白俄罗斯语：Бабруйск）是位于白俄罗斯中部莫吉廖夫州别列津纳河畔的一座城市，人口约227,000（2000年）。

Babruysk, Bobruysk, or Bobruisk (Belarusian:Бабру́йск, Łacinka: Babrujsk, Russian:Бобру́йск, Polish:Bobrujsk, Yiddish:באברויסק‎) is a city in the Mogilev Region of eastern Belarus on the Berezina river. It is a large city in Belarus. As of 2009, its population was 215,092. The name Babruysk (as well as that of the Babruyka River) probably originates from the Belarusian word babyor (бобёр) (beaver), many of which used to inhabit the Berezina. However, beavers in the area have been almost eliminated by the end of the 19th century due to hunting and pollution.