乌卡亚利河（西班牙语：Río Ucayali）发源自南美洲阿雷基帕大区的的喀喀湖以北110公里（70英哩），河道全长1,600.1公里，是亚马逊河豚、巨獭和亚马逊海牛的栖息地。秘鲁乌卡亚利大区以乌卡亚利河命名。

The Ucayali River (Spanish:Río Ucayali, IPA: [ˈri.o ukaˈʝali]) arises about 110 km (68 mi) north of Lake Titicaca, in the Arequipa region of Peru. The Amazon River takes its name close to Nauta city (100 km upstream/south of Iquitos), at the confluence of the Marañón and Ucayali rivers. The Ucayali becomes a major tributary of the Amazon River. Navigation was blocked by lengthy sections of rapids. The city of Pucallpa is located on the banks of the Ucayali.