Oxidation of tropine with chromic oxide gave tropinone which can be quaternized to 5 in quantitative yield. 为了使反应的研究简化,将阿托品水解为托品醇、再氧化为托品酮,托品酮季胺盐与氢化钠反应。
Tropine is a derivative of tropane containing a hydroxyl group at third carbon. It is also called 3-tropanol.
Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.