传染性貂脑病（英语：Transmissible mink encephalopathy，缩写为TME），传染性海绵状脑病的一种，由普利昂蛋白引起，会侵袭由人类饲养长大的貂，破坏它的中枢神经系统。目前已知只有成年的貂会罹患这个疾病，潜伏期是7个月至12个月，罹患的貂将会死亡。目前没有检验方法，可以知道活体动物是否患病，只能透过死后的解剖来加以确认。

Transmissible mink encephalopathy (TME) is a rare sporadic disease that affects the central nervous system of ranch-raised mink. It is classified as a transmissible spongiform encephalopathy, believed to be caused by proteins called prions. This disease is only known to affect adult mink.