Now, the acute attacks are likely due to the build up of the toxic metabolites.

急性发作可能是由于有毒代谢物的累积。

Toxic metabolites also affect the autonomic nervous system regulating gastrointestinal motility, and this can causes abdominal pain, constipation, and vomiting.

毒性代谢产物也可以影响调节胃肠蠕动的自主神经系统，可以导致腹痛、便秘和呕吐。

So first, less blood gets to the liver, causing diminished liver function and decreased blood detoxification, which leads to a buildup of toxic metabolites, like ammonia in the blood.

所以首先，回到肝脏的血流减少导致肝功能下降、分解血液中毒素的能力下降，进而导致毒性代谢产物的生成，例如血氨。

And when it does, the toxic metabolites of methanol may potentially worsen the hangover symptoms. Beverages that are closer to pure ethanol, such as gin and vodka, may cause fewer hangover effects.

当它发生时，甲醇的有毒代谢物可能会加重宿醉症状。杜松子酒和伏特加等更接近纯乙醇的饮料可能会导致较少的宿醉效应。