塞斯普罗蒂亚州（希腊语：Θεσπρωτία）是希腊伊庇鲁斯大区西北部的一个州，位于品都斯山脉西麓沿岸，西北邻阿尔巴尼亚，西隔克基拉海峡与科孚岛相望。面积1,515平方公里，2005年人口46,811人。首府伊古迈尼察。

下分8市、2镇。

Thesprotia (/θɛsˈproʊʃə/; Greek:Θεσπρωτία) is one of the regional units of Greece. It is part of the Epirus region. Its capital is the town of Igoumenitsa. It is named after the Thesprotians, an ancient Greek tribe that inhabited the region in antiquity.