Also, another distinction from ulcerative colitis is that these areas of inflammation are scattered as opposed to being continuous, and have areas of healthy tissue interspersed between inflamed areas, this gives it a " cobblestone appearance" .

与溃疡性结肠炎的另一个区别是克罗恩病的炎症区域是分散的，而溃疡性结肠炎的病灶则是连续性的；克罗恩病的炎症病灶之间有散在的正常组织区域，这就形成了“铺路石样外观”。