圣玛尔塔（西班牙语：Santa Marta）位于哥伦比亚北部加勒比海沿岸，是马格达莱纳省的首府，人口约41万（2002年）。

圣玛尔塔是重要的海港城市，也是著名的旅游、历史和文化中心。

拉丁美洲革命家西蒙·玻利瓦尔于1830年12月17日在圣玛尔塔逝世。

Santa Marta is a city in Colombia. It is the capital of the department of Magdalena and third largest urban city of the Caribbean Region of Colombia, after Barranquilla and Cartagena. Founded on July 29, 1525, by the Spanish conquistador Rodrigo de Bastidas, it was the first Spanish settlement in Colombia, and is the oldest surviving city in that country, and second oldest in South America. This city is situated on a bay of the same name and as such, is a prime tourist destination.