Salaparuta is a town and comune in South-Western Sicily, Italy, in the valley of the Belice river, administratively part of the province of Trapani. It had 1,781 inhabitants as of 2007.

In 1968 the original site of the town was near epicentre of the Belice Valley earthquake. As a result, Salaparuta was completely destroyed and rebuilt not far from the original location. The current Salaparuta is still home to many of the citizens of the old town.