Acrosin
![](/Images/godic/202412/20/1FIW1321.png")
![Acrosin catalytic mechanism](/Images/godic/202412/20/Acrosin_Catalytic_Mechanism1321.jpg")
![Acrosin active site surface contour, shown with competitive inhibitor benzamidine. Trp-215](/Images/godic/202412/20/1FIW_Active_Site_Surface1321.png")
![Acrosin active site residues, shown with competitive inhibitor benzamidine.](/Images/godic/202412/20/1FIW_Active_Site_Residues1321.png")
Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene. Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.