A planar tetradentate dinuclear ligand, 3, 5-bis(2-pyridyl) pyrazole, was synthesized by a three-step reaction of esterification, condensation and addition. 以2-吡啶甲酸为原料,经酯化、缩合、加成合成了平面四齿双核配体3,5-二(2-吡啶基)吡唑。
Among of them, indoles and pyrazoles are of great importance and they are also hotspots that organic chemists are researching. 吲哚和吡唑是含氮有机杂环化合物的两大类型,它们也是有机化学家研究的热点问题。
Pyrazole is an organic compound with the formula C3H3N2H. It is a heterocycle characterized by a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C). Pyrazoles are also a class of compounds that have the ring C3N2 with adjacent nitrogen atoms. A notable drug containing a pyrazole ring is celecoxib (Celebrex).