Plasminogen activator inhibitor-2
（重定向自Plasminogen activator inhibitor 2）
![](/Images/godic/202502/03/Protein_SERPINB2_PDB_1by73056.png")
![](/Images/godic/202502/03/PBB_GE_SERPINB2_204614_at_tn3056.png")
![Fibrinolysis (simplified). Blue arrows denote stimulation, and red arrows inhibition.](/Images/godic/202502/03/Fibrinolysis3056.png")
![](/Images/godic/202502/03/PDB_1by7_EBI3056.jpg")
Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form.