Phytolaccaceae is a family of flowering plants. Such a family has been almost universally recognized by taxonomists, although its circumscription has varied. It is also known as the Pokeweed family.

The APG II system, of 2003 (unchanged from the APG system, of 1998), also recognizes this family and assigns it to the order Caryophyllales in the clade core eudicots. The family comprises about 16 genera, totalling a hundred species. It is divided into the subfamilies Agdestioideae, Phytolaccoideae, and Rivinioideae by the Takhtajan system.