If the brain already has opiate receptors, doesn`t that mean it can naturally provide pain relief?
如果大脑已经有了阿片受体,那不就意味着它可以自然地缓解疼痛吗?
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After being injected, the drug crosses the blood-brain barrier, where it binds to opiate receptors and causes a brief high described as being similar to that of heroin.
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs). Opioid receptors are distributed widely in the brain, and are found in the spinal cord and digestive tract.