Nissl body
![Image of a Nissl-stained histological section through the rodent hippocampus showing various classes of cells (neurons and glia).](/Images/godic/202501/29/NisslHippo22154.jpg")
![Motor nerve cell from ventral horn of medulla spinalis of rabbit. The angular and spindle-shaped Nissl bodies are well shown.](/Images/godic/202501/29/Gray6262154.png")
A Nissl body, also known as Nissl substance, is a large granular body found in neurons. These granules are of rough endoplasmic reticulum (RER) with rosettes of free ribosomes, and are the site of protein synthesis. It was named after Franz Nissl, a German neuropathologist who invented the Nissl staining method.