马斯科卡区域自治市（District Municipality of Muskoka，简写为District of Muskoka或Muskoka），又译穆斯科卡区域自治市，是位于加拿大中安大略的一个自治区。马斯科卡区西临格鲁吉亚湾，南面为Couchiching湖，东接阿尔冈金省立公园。马斯科卡区离多伦多北面大约需要2个小时，总面积为6,475 km（2,500 sq mi）。马斯科卡区有大约1,600个湖泊，是著名的旅游胜地。

马斯科卡区和哈利伯顿、卡沃瑟湖区及佩得伯勒县都被称为“乡村度假村”（cottage country），每年有超过210万访客。马斯科卡区政府位于布雷斯布里奇。

The District Municipality of Muskoka, more generally referred to as the District of Muskoka or Muskoka, is a Regional Municipality located in Central Ontario, Canada. Muskoka extends from Georgian Bay in the west, to the northern tip of Lake Couchiching in the south, to the western border of Algonquin Provincial Park in the east. Located approximately a two-hour car drive north of Toronto, Muskoka spans 6,475 km (2,500 sq mi). Muskoka has some 1,600 lakes, making it a popular cottaging destination.