Peyote

Lophophora williamsii /loʊˈfɒfərə wɪlˈjæmsiaɪ/ or peyote (/pəˈjoʊti/) is a small, spineless cactus with psychoactive alkaloids, particularly mescaline. The English common name peyote comes from the like-spelled Spanish name, which in turn comes from the Nahuatl name peyōtl [ˈpejoːt͡ɬ], said to be derived from a root meaning "glisten" or "glistening". Other sources translate the Nahuatl word as "Divine Messenger". Native North Americans are likely to have used peyote, often for spiritual purposes, for at least 5,500 years.