The extraglomerular mesangial cells help with the signalling between macula densa cells and juxtaglomerular cells.
球外系膜细胞辅助致密斑和球旁细胞的信息传递过程。
Osmosis-泌尿
In response to this high-pressure state, the supportive mesangial cells secrete more and more structural matrix expanding the size of the glomerulus.
为了应对这种高压力状态,系膜细胞分泌更多的细胞外基质,增大了肾小球体积。
Osmosis-泌尿
These growth factors cause the mesangial cells to regress back to their more immature stem cell state known as mesangioblasts and secrete extracellular structural matrix.
这些生长因子使得系膜细胞退化成为未成熟的干细胞状态(成系膜细胞),并分泌细胞外基质框架。
Osmosis-泌尿
On light microscopy, there'll often be mesangial proliferation, or expansion of the mesangium, and upon getting a closer look with electron microscopy, there'll be immune complexes deposited within the mesangium.
In the glomerulus of the kidney, the mesangium is a structure associated with the capillaries. It is continuous with the smooth muscles of the arterioles. It is outside the capillary lumen, but surrounded by capillaries. It is in the middle (meso) between the capillaries (angis). It is contained by the basement membrane, which surrounds both the capillaries and the mesangium.