管理信息系统（Management Information System，MIS）是一个以人为主导的，利用计算机硬件、软件和网络设备，进行信息的收集、传递、存储、加工、整理的系统，以提高组织的经营效率。

管理信息系统是有别于一般的信息系统，因为它们都是用来分析其它信息系统在组织的业务活动中的应用。学术上，管理信息系统通常是用来指那些和决策自动化或支持决策者做决策有关的信息管理方法（例如决策支持系统，专家系统，和主管支持系统）的统称。

A management information system (MIS) focuses on the management of information systems to provide efficiency and effectiveness of strategic decision making. The concept may include systems termed transaction processing system, decision support system, expert system, or executive information system. The term is often used in the academic study of businesses and has connections with other areas, such as information systems, information technology, informatics, e-commerce and computer science; as a result, the term is used interchangeably with some of these areas.