These centroblasts have a rearrangement of their immunoglobulin genes, and some of them undergo a class switch where they change from producing IgM antibodies to producing IgG or IgA antibodies.

这部分中心母细胞的免疫球蛋白基因发生了重排，其中的一些会经历Ig类别转换，从产生IgM变成产生IgG或IgA。