Mestranol/noretynodrel

Mestranol/noretynodrel was the first combined oral contraceptive pill (COCP) being mestranol and noretynodrel (INNs). It sold as Enovid in the United States and as Enavid in the United Kingdom. Developed by Dr. Gregory Pincus at G. D. Searle & Company, it was first approved on June 10, 1957 by the U.S. Food and Drug Administration for treatment of menstrual disorders. The FDA approved an additional indication for use as a contraceptive on June 23, 1960. In 1961, it was approved as a contraceptive in the UK and in Canada.