eIF2
![The process of initiation of translation in eukaryotes with eIF2 in light-green. Other factors are shown, too.](/Images/godic/202501/10/Eukaryotic_initiation2744.png")
![Regulation of translation initiation via phosphorylation of Ser51 in eIF2's α-subunit.[8]](/Images/godic/202501/10/EIF2regulation2744.jpg")
Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor. It is required in the initiation of translation. eIF2 mediates the binding of tRNAi to the ribosome in a GTP-dependent manner. eIF2 is a heterotrimer consisting of an alpha (also called subunit 1), a beta (subunit 2), and a gamma (subunit 3) subunit.